Serena is the substitute guardian of Lissa. She works alongside Grant in protecting Lissa. When Lissa visits Lehigh, Grant and Serena accompany her along with guardians for Priscilla Voda and Christian Ozera. Grant, Priscilla and the other guardians are all murdered, and Serena is left in very bad shape, however she is able to call back to the Royal Court guardians and tell them what happened. Serena also aids Lissa and Christian, with Grant, to train with stakes and in fighting Strigoi. Serena helps Lissa find Tatiana's murderer in Last Sacrifice.

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